Biomimetic nanostructures

Biomimetic nanomaterials

 There is significant current interest in bio-mimetic synthesis as technologies to underpin the development of processes which are modular, scalable and crucially accessible to the broad materials community. The state of the art research, such as DNA nanotechnology (nanoscale fabrication using DNA building blocks) and DNA templated synthesis (in vitro replication, transcription and translation using DNA templates) currently all have a complete reliance on biological polymers . These approaches are primarily biokleptic wherein biological polymers such as nucleic acids are harvested directly (or copied with identical molecular structure) from nature’s toolbox in pursuit of controlled synthesis or replication. Ultimately, such a templating approach is limiting, especially when one considers inherent constraints in biological polymers such as limited building block functionality, instability in synthetic media such as non-native pH and/or ion concentrations, limited bioavailability, possible immunogenicity issues in therapeutic applications and limited scalability and, thus accessibility.