Current Members

Group Leader

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Prof. Rachel O'Reilly

Office: 2.14b
Lab: 7th floor
Email: r.oreilly@bham.ac.uk

Find our more about Rachel here.

Senior Research Fellows

Amanda Pearce

Amanda Pearce

Amanda was born and raised in Dalby, Australia. She obtained a BSc with First Class Honours in Chemistry from the University of Queensland in 2011, with her final year project within the lab of Assoc. Prof. Kristofer Thurecht and Prof. Andrew Whittaker. She then remained in the same research group to pursue her PhD, graduating in 2015. Her thesis focused on the development and synthesis of drug-loaded hyperbranched polymer nanoparticles via controlled radical polymerisation techniques, with active targeting abilities for in vivo imaging and drug delivery towards prostate cancer applications. She then moved to the group of Prof. Cameron Alexander at the University of Nottingham in 2016 as a Research Fellow within the EPSRC funded ‘Next Generation Biomaterials Discovery’ grant, where she focused on the design, synthesis and characterisation of bespoke novel synthetic polymers through various synthetic strategies (RAFT, ROP etc) for in vivo drug delivery, with a particular interest in how choice of chemistry, architecture and size can be tuned to direct nanoparticle delivery in the body. In 2019, Amanda moved to Birmingham to join the O’Reilly group as a Senior Research Fellow.


Email: A.K.Pearce@bham.ac.uk

Post-Doctoral Researchers

AS

Amrita Sikder

Amrita received her B.Sc. degree in chemistry from Calcutta University (India) in 2011 and M.Sc. degree from Indian Institute of Technology Madras (department of chemistry) in 2013. Then she joined the laboratory of Prof. Suhrit Ghosh at Indian Association for the Cultivation of Science (IACS-Kolkata) in School of Applied and Interdisciplinary Sciences to pursue her PhD degree. Her PhD work was focused on establishing suitable supramolecular strategies based on H-bonding for directional assembly of π-amphiphiles with designer’s control on their morphology, functional group display, charge density and other properties and correlating with their multivalent interaction with bio-macromolecules such as proteins. In August 2019, she moved to UK and joined the O’Reilly group as a post-doctoral researcher. Her research project is focused on RNA delivery system based on a supramolecular and polymeric assembly.

Email: A.Sikder.1@bham.ac.uk

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Jennifer Frommer

Jennifer was born and raised in Berlin, Germany. She received her Diploma degree in Biochemistry from the University of Greifswald in 2012 and afterwards started her PhD thesis in the Department of Biochemistry in the laboratory of Prof. Sabine Müller specialising in nucleoside chemistry and RNA engineering. During her PhD work she achieved the synthesis of various new nucleoside analogues by multi-step synthesis, which were used for functionalizing diverse RNA strands. This enabled the investigation of a reductive charge transfer through RNA duplex and functional RNA aptamer structures, as well as the evaluation of new RNA probes for structural spectroscopic methods. In January 2020, she moved to the UK and joined the O’Reilly group as a post-doctoral researcher. Her research project is focused on DNA-templated chemistry, which is one of the key steps for the development of an artificial ribosome – a molecular machine capable of making sequence-defined polymers according to a genetic program.

Email: J.Frommer@bham.ac.uk

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Sam Parkinson

Sam was born in Bolton but grew up in Lincolnshire. He obtained his MChem degree from the University of York in 2016. His masters project investigated the capture and release of aldehyde-based fragrances from supramolecular hydrogels. In October 2016, he began a PhD in Chemical Engineering under the supervision of Dr. Nicholas Warren. His work focused on the synthesis of polymeric materials in tubular flow reactors. In addition, Sam incorporated analytical techniques, such as NMR & GPC, into flow platforms in order to develop autonomous self-optimising systems. After obtaining his PhD in July 2020, Sam joined the O’Reilly group as a post-doctoral researcher. His research project involves developing polymeric nano-particles for use as biological sensors in plants.

Email: S.J.Parkinson@bham.ac.uk

Stephen Fielden

Stephen Fielden

Born in Bury, Greater Manchester, Stephen earned his MChem from the University of Oxford, working with Prof. Véronique Gouverneur during his Part II year. His PhD, supervised by Prof. David Leigh at the University of Manchester, concerned the construction of interlocked molecules (rotaxanes, catenanes and knots) and developing new molecular machinery. He then continued in Prof. Leigh’s laboratory with a postdoctoral research position. Stephen’s experience spans supramolecular and non-equilibrium systems chemistry. He joined the O’Reilly Group as a Research Fellow in January 2021.

Email: S.Fielden@bham.ac.uk

PhD Students

Final Year

Maria Pervez

Maria was born in Pakistan, done her early studies there and was awarded Gold Medal at UG level. She graduated with 1st Class M.Sc. and M.Phil. degrees from the Quaid-i-Azam University, Islamabad in 2014 and 2016, respectively. Her M.Phil. research project was based on hydrogen production by water splitting using transition metals deposited nanomaterials. She then worked as Research Associate at Allama Iqbal Open University, Islamabad for 1 year. In October 2017, she started her Ph.D. under the supervision of Prof. Rachel O’ Reilly. Her work is focused on the preparation and characterization of biocompatible fluorescent particles.

Email: MXP799@student.bham.ac.uk

4th Year
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Marjolaine Thomas

Marjolaine was born in France and obtained her Bachelor degree in Materials Chemistry from the University of Bordeaux in 2016. She continued her studies at the University of Bordeaux where she obtained a masters degree in Advanced Materials in 2018. During her masters degree she undertook an Erasmus placement at the University of Helsinki and did an internship under the supervision of Prof. Heiki Tenhu working on drug delivery systems using RAFT polymerization. During her second year she went back to Bordeaux for a semester. Then, she completed her master thesis at the University of Montréal in the group of Géraldine Bazuin working on the self-assembly of block-copolymers on PDMS substrates. In October 2018, Marjolaine has joined the group and started her PhD under the supervision of Prof. Rachel O’Reilly and her work will be focused on the Biomimetic polymerization-induced self-assembly and DNA.

Email: MXT884@student.bham.ac.uk

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Simon Dale

Simon is from Cheshire and completed his BSc and MSc in Chemistry at University of Liverpool. He undertook his MSc research project under Professor Steve Rannard with the primary aim towards synthesising hyper-branched polydendrons using free radical polymerisation. The second aim of his project was to show that thiol chain transfer agents could be made in-situ prior to polymerisation via de-protection of a masking xanthate group. After completion of his Masters degree, Simon worked for Perstorp in Warrington researching and synthesising polycaprolactone by ring opening polymerisation for use as additives, blends and biodegradable thermoplastics. In October 2018, he started his PhD under the supervision of Professor Rachel O’Reilly and Professor Andrew Dove investigating polyester containing block co-polymers and their self-assembly in oil

Email: SXD802@student.bham.ac.uk

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Cinzia Clamor

Cinzia was born in Germany and obtained her BSc in Chemistry from the University of Münster in 2016. She then continued her studies at the University of Münster and graduated with a masters degree in Chemistry in 2018. During her masters studies she undertook an Erasmus placement at the University of Bath in the group of Prof. Stephen Husbands working on the design and synthesis of compounds targeting G-coupled receptor kinase. Then, she completed her master thesis under the supervision of Prof. Gustavo Fernández at the University of Münster with the focus on the synthesis and self-assembly behaviour of fluorescent BODIPY-based structures for biomedical applications. In October 2018, she started her PhD under the joint supervision of Prof. Andrew Dove and Prof. Rachel O’Reilly working on the synthesis and self-assembly of oil soluble polyesters.

Email: cxc1023@student.bham.ac.uk

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Eirini Epitropaki

Eirini was born and raised in Crete, Greece where she did her BSc at the University of Crete in Material Science. Her Bachelor Thesis was on drug delivery systems of supramolecular biohybrids of protein-polymer. She continued her studies in Aristotle University of Thessaloniki where she obtained an MSc degree in Nanoscience and Nanotechnology. Her Master Thesis was conducted in the Foundation for Research and Technology Hellas (FORTH), where she worked on the European NanoREG project concerning nanosafety measurements and characterization of nanoparticles and on synthesis of graphene oxide hydrogels for tissue engineering applications. In October 2018, she started her PhD under the supervision of Professor Rachel O’Reilly and Professor Andrew Dove, where she will develop drug delivery systems for neural stem cell proliferation in the brain as part of NANOSTEM program.

Email: EXE896@student.bham.ac.uk

IremAkar

Irem Akar

Irem was born in Istanbul, Turkey. She graduated from Marmara University in 2015 with a BSc degree in Bioengineering. She then obtained an MSc degree in Biotechnology at Bezmialem Vakif University in 2018. Her studies were focused on light-responsive DNA-polymer and protein-polymer conjugates to be used as smart drug delivery systems. She has started her PhD in January 2019 under the supervision of Prof Rachel O’Reilly to study stimuli-responsive polymeric nanoparticles for drug delivery applications.

Email: IXA849@student.bham.ac.uk

3rd Year
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Alisha Miller

Alisha is from Wokingham and completed her MChem in Chemistry at the University of York. During a break in her studies, she worked at a global medical device company where she coordinated material verification and developed testing methods for new regulatory standards. For her fourth year masters project she worked out in industry in the Composites Global Business Unit of Solvay. Her project involved investigating the rheological properties of uncured epoxy resin and thermoplastic mixtures for use in the aerospace industry. In September 2019, Alisha started her PhD in Chemistry under the supervision of Prof. Rachel O’Reilly; her work is focussed on the development of nanoreactors by polymerization-induced self-assembly (PISA) for biomedical applications.

Email: AXM1627@student.bham.ac.uk

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Siriporn 'Snook' Chaimueangchuen

Snook was born in Thailand and obtained her Bachelor degree in Chemistry from Chiang Mai University in 2016. Her bachelor project focused on synthesis and preparation of injectable hydrogel based on stereocomplexed polylactide. She studied her Master degree at Chulalongkorn University in Polymer science under the supervision of Prof. Suwabun Chirachanchai. In Master’s thesis, she was working on molecular design and synthesis for supramolecular molecule i.e. [3]Psuedorotaxane. In October 2019, Snook has joined the group and started her PhD under the supervision of Prof. Rachel O’Reilly and her work will be focused on the Polymerization-Induced Self-Assembly(PISA) and DNA in a small volume.

Email: SXC1216@student.bham.ac.uk

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BEN ALLOT

Ben was born in Winchester and competed his MSci in Chemistry at the University of Nottingham. The bachelor component of his degree spanned a variety of topic from solving advanced differential equations to medicinal chemistry. He completed various projects in organic, inorganic, and physical labs throughout his bachelors; in his masters he worked under Prof. James Dowden where he was working on a novel, convergent synthetic route to a natural opioid: Mitragynine pseudoinoxyl. He started his PhD in March 2020 under Prof. Rachel O’Reilly where he is working on DNA template synthesis – a method of programmable, autonomous, sequence specific synthesis.

Email: BBA911@student.bham.ac.uk

2nd Year
Jess Hawkins

JESS HAWKINS

Jess was born in Bristol but grew up in Cornwall. She moved to Birmingham for her undergraduate studies, during which she travelled to Basel in Switzerland for a year in industry. Here she interned with Roche working on a project developing small molecules for the treatment of Progressive Multiple Sclerosis. Jess’s MSci Chemistry degree included a final-year project with the Cox Group working on the synthesis of phenyltriazolinedione derivatives for the bioconjugation of proteins. Her PhD on DNA-templated chemistry uses DNA in the synthesis of oligonucleotides.

Email: JRH619@student.bham.ac.uk

1st Year
David Londoño

DAVID LONDOÑO

David is from Cartagena de Indias in Colombia, and has also lived in Spain. He earned his Bachelor’s degree in Chemistry at the University of Zaragoza, supervised on his thesis 'Synthesis of New hole-transporters for perovskite solar cells applications' by Dr Santiago Franco Ontaneda. His Master’s degree in Industrial Chemistry, supervised by Dr Elena Piera Camas and in collaboration with Nurel Engineering Polymers SA, resulted in the thesis 'Synthesis and Study of properties of new polyamide 6 Nanocomposite polymers type for injection applications'. David worked as an R&D Laboratory Technician at Nurel Engineering Polymers for three years. He joined the O’Reilly Group as a PhD student in early 2021; his studies are supported by the BP Pelican project, which aims to use polymer-based solutions to improve reservoir sweep.

Email: DAL018@student.bham.ac.uk

Rachel Stracey

RACHEL STRACEY

Lancastrian Rachel studies Chemistry to contribute to a sustainable future through the development of new materials. She graduated with a Master of Chemistry from the University of York – her Master’s research project was completed in Prof. Duncan Bruce’s group and was titled: “An investigation into the introduction of perfluorinated chains into the structure of discotic luminescent gold(III) complexes and their effects on mesophase behaviour”. Rachel joined the O’Reilly Group in June 2021 to research crystalline-driven self-assembly and fluorescent barcoding.

Email: RFS146@student.bham.ac.uk

Beth Crow

BETHANY CROW

Beth joins the O’Reilly Group as a new PhD researcher in 2021. A native of Hull, her research interest centres on toxicology, and her PhD will investigate nanoparticles for biomedical application. Beth’s MChem and BSc in Chemistry with a Year in Industry were earned at the University of Leeds. Her masters project was on the Structure Activity Relationships of Quinolines (antimalarials) with an artificial biomembrane screening platform (membrane-on-a-chip), pioneered by Professor Andrew Nelson. Beth is a keen dancer and dog lover.

Email: BXC187@student.bham.ac.uk

Jake Barker

JAKE BARKER

Jake is from Bristol, and his studies have taken him to Wales and Canada. On his Integrated MChem at Cardiff University with Professor Angela Casini, he developed metal NHC-complexes to prevent DNA replication in cancers. Jake’s year abroad at the University of Toronto Mississauga with the Gunning Group involved the development of electrophilic warhead molecules for the disruption of cancer proliferation. His PhD investigating the precision self-assembly of polymers builds towards Jake’s interest in medicinal applications. He enjoys live music.

Email: JXB1408@student.bham.ac.uk

Phillippa Edge

PHILLIPPA EDGE

Phillippa has lived in Bedford, Cambridge, and Durham, where she earned her MChem. Her Masters Project took place in the Functional Surface Research group, and was based around metal-organic frameworks and the functionalisation of surfaces with biopolymers. Most recently, Phillippa worked in R&D at US biotechnology company Illumina, investigating patterned flowcell technology. Her PhD in the O’Reilly Group will focus on DNA. Phillippa enjoys camping and playing squash.

Email: PKE178@student.bham.ac.uk

Laihui Xiao

LAIHUI XIAO

Laihui is a graduate of Fujian Normal University – where he researched recycled PET during his BEng majoring in Polymer Materials and Engineering – and of the Chinese Academy of Forestry, from where he earned an MEng focused on modifying commercial epoxy resin with bio-based materials. He has most recently worked as a research assistant investigating bio-based functional polymeric materials. Laihui’s research in the O’Reilly Group will concentrate on the synthesis of complex, degradable and functional polymeric nanoparticles by the method of crystallization driven self-assembly (CDSA). Laihui enjoys cycling, table tennis, and running.

Email: LXX115@student.bham.ac.uk

MSci students

Aine Cunningham

Aine Cunningham

Aine is a current MSci student at the University of Birmingham, and has also lived in Manchester and Tenerife. After completing a project in her third year on combatting antibiotic resistance using antimicrobial polymers, Aine’s current research in the O’Reilly Group investigates the creation of materials that are useful in medical and materials applications.

Email: AXC1054@student.bham.ac.uk